Understanding the embryonic origins of cortical malformations

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1063080

Funding Status
Closed

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Funded Activity Summary

Cortical malformation leads to mental retardation and epilepsy. Identification of the aberrant developmental processes contributing to these devastating syndromes is essential for accurate clinical assessment and development of novel therapeutics. Here we investigate a developmentally important receptor, Neogenin, which when mutated, leads to cortical malformations. Determining how Neogenin functions is expected to uncover new signaling pathways contributing to these malformations.

Funded Activity Details

Start Date: 01-01-2014

End Date: 01-01-2017

Funding Scheme: Project Grants

Funding Amount: $815,228.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Cellular Nervous System

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

cortical development | epilepsy | mental retardation | neural development | neural stem cell | neurobiology | neurodevelopmental disorders | neurogenesis | neuronal differentiation | neuronal migration

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