Defining pathogenic mechanisms of intracellular bacteria

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1062383

Funding Status
Closed

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Funded Activity Summary

This study explores how the bacterium Coxiella burnetii causes the serious infectious disease Q fever. Coxiella is a potential biological weapon because it is very stable in the environment and few organisms are required to cause disease. Coxiella is able to commandeer human cells to replicate in a specialized vacuole but little is understood about how they do this. We will examine the virulence factors of Coxiella and investigate how they allow the bacteria to replicate inside human cells.

Funded Activity Details

Start Date: 01-01-2014

End Date: 01-01-2016

Funding Scheme: Project Grants

Funding Amount: $494,691.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Medical Bacteriology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Coxiella burnetii | Q fever | intracellular bacterial infections | lysosome biology | molecular pathogenesis | pathogenesis | pathogenic bacteria | pathogenic mechanisms | vesicle trafficking | virulence factors

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