Targeting translational control by modulating miRNA function as a novel way to treat respiratory infections and inflammatory disease

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1062278

Funding Status
Closed

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Funded Activity Summary

Among the major health issues of today is our inability to effectively treat bacterial infections and the emergence of antibiotic resistant microbes. MicroRNA are small molecules that control the levels of proteins in immune cells that fight infections. In this project we will determine if inhibiting miRNA function in the lung enhances defence against microbial invasion and is a new therapeutic approach to treat infection driven diseases of the airways such asthma and emphysema.

Funded Activity Details

Start Date: 01-01-2014

End Date: 01-01-2017

Funding Scheme: Project Grants

Funding Amount: $700,623.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Respiratory Diseases

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

asthma | asthma exacerbation | infection | innate immunity | interleukins (IL) | microrna

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