Revealing how the mammalian preimplantation embryo undergoes compaction

Funding Activity

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Funded Activity Summary

The first morphological process critical for mammalian development is embryo compaction. During compaction, cells change their morphology from rounded to wedge-like. The mechanisms controlling embryo compaction remain unclear. We recently discovered that during compaction, cells extend long membrane protrusions on top of each other. In this Project we will establish the role of these protrusion in controlling embryo compaction and reveal the mechanisms underlying their formation.

Funded Activity Details

Start Date: 01-01-2014

End Date: 01-01-2017

Funding Scheme: Project Grants

Funding Amount: $705,102.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Cell Development, Proliferation and Death

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

cell biology | cell polarity | developmental biology | imaging | mouse models