Roles for gastrin and hypoxia in colorectal carcinogenesis

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1062173

Funding Status
Closed

Does something not look right? The information on this page has been harvested from data sources that may not be up to date. We continue to work with information providers to improve coverage and quality. To report an issue, use the .

Funded Activity Summary

Our objective is to understand how hormones such as gastrin stimulate the development of colorectal cancer. Our preliminary data shows that the amount of gastrin produced by tumour cells is increased by low oxygen. We will therefore study how the increase in gastrin in response to low oxygen causes a compensatory growth of the tumour. The ability to interfere with this process should allow us to slow tumour growth.

Funded Activity Details

Start Date: 01-01-2014

End Date: 01-01-2016

Funding Scheme: Project Grants

Funding Amount: $636,508.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Gastroenterology and Hepatology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

colorectal cancer | gastrin | gastrointestinal tumourigenesis | growth factor | hypoxia | regulatory peptides

Related Links