Combining immune monitoring and immunotherapy to tackle cytomegalovirus infections in solid organ transplant patients

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1062074

Funding Status
Closed

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Funded Activity Summary

Clinical management of infectious complications in kidney and heart/lung transplant patients remains significant challenge. Although prophylactic/pre-emptive treatment with antiviral drugs have shown dramatic improvements in the control of these infections, long-term treatment with these drugs is associated with significant toxicity, the appearance of drug-resistant virus isolates and significant health cost. In this proposal we will develop novel strategies to identify high risk patients and treat these patients with killer T cells.

Funded Activity Details

Start Date: 01-01-2014

End Date: 01-01-2017

Funding Scheme: Project Grants

Funding Amount: $801,416.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Transplantation Immunology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

T cell immunotherapy | cytomegalovirus (CMV) infection | immune surveillance | immunotherapy | transplant recipients

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