Investigation of the mechanism by which medium chain fatty acids prevent the development of obesity and insulin resistance - what role for GPR84?

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1061804

Funding Status
Closed

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Funded Activity Summary

Medium chain fatty acids do not induce the same degree of obesity and insulin resistance as long chain fatty acids and this is due to changes in metabolism in skeletal muscle and adipose tissue. In this proposal we will investigate whether medium chain fatty acids induce their beneficial effects by interacting with a specific G protein-coupled receptor named GPR84. This receptor may be a new therapeutic target for the treatment of metabolic diseases.

Funded Activity Details

Start Date: 01-01-2014

End Date: 01-01-2016

Funding Scheme: Project Grants

Funding Amount: $512,541.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Endocrinology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

G protein-coupled receptors | energy metabolism | insulin action | mitochondrial function | obesity | oxidative stress

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