Optimising combinations of calcium channel inhibitors for treatment of secondary degeneration after neurotrauma

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1061791

Funding Status
Closed

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Funded Activity Summary

Traumatic injury to the central nervous system is made worse by damage that spreads away from the initial point of impact. Excess calcium entering cells is a key contributor to spreading damage but treatment with single calcium channel inhibitors has been disappointing. We will use combinations of calcium channel inhibitors to block multiple calcium channels and ensure the optimised combination is effective in clinically relevant models of neurotrauma.

Funded Activity Details

Start Date: 01-01-2014

End Date: 01-01-2016

Funding Scheme: Project Grants

Funding Amount: $679,772.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Central Nervous System

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

calcium | calcium channels | inhibitors | neurotrauma | oxidative stress | spinal cord injury

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