Probing the Cardiac Gene Regulatory Network in Development and Congenital Heart Disease

Funding Activity

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Funded Activity Summary

In Australia, congenital heart disease (CHD) is the biggest killer of children under 5 years. Defects range from small holes to severe malformations requiring multiple surgeries and an uncertain future. Our appreciation of CHD mechanism is limited. Using cutting-edge technologies in genomics, biophysics and structural biology, we will study the mechanisms that lead to CHD at unprecedented resolution. Our project will progress the concept of personalized diagnosis and treatment of CHD.

Funded Activity Details

Start Date: 01-01-2014

End Date: 01-01-2016

Funding Scheme: Project Grants

Funding Amount: $518,118.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Genome Structure and Regulation

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

developmental biology | heart development | heart disease | mouse models | transcription factor | transcriptional regulation