Dissecting the role of RYK in cortical neuron specification and schizophrenia

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1061512

Funding Status
Closed

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Funded Activity Summary

Correct production of neuronal subtypes within the neocortex is essential for coordinated brain activity and higher-order functions. Understanding how newborn neurons decide which subtype to adopt is critical as incorrect neuron identity has profound consequences for neocortical function and is associated with schizophrenia and mental disability. We have recently linked one molecule, RYK, to schizophrenia. In this project we will explore how Ryk influences cortical neuron fate.

Funded Activity Details

Start Date: 01-01-2014

End Date: 01-01-2016

Funding Scheme: Project Grants

Funding Amount: $1,039,028.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Cellular Nervous System

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

axon growth | axon guidance | cortical development | neural development | neural stem cell | neurobiology | neurodegenerative disorders | neurogenesis | neuronal differentiation | schizophrenia and related disorders

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