Targeting the hypoxia sensing pathway to improve hematopoietic stem cell mobilisation and transplantation

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1061333

Funding Status
Closed

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Funded Activity Summary

Transplantation of patients’ own blood stem cells is used to treat many blood cancers. It increases the chance of cure. However the damage caused by chemotherapies used to combat the cancer can compromise stem cell collection and transplantation. Without transplant, these patients are less likely to survive cancer. This project is to test new drugs that enhance the harvest of blood stem cells for transplantation. These will increase the success rates of transplants and cure in these cancer patients.

Funded Activity Details

Start Date: 01-01-2014

End Date: 01-01-2016

Funding Scheme: Project Grants

Funding Amount: $653,313.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Cellular Interactions (incl. Adhesion, Matrix, Cell Wall)

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

bone marrow reconstitution | cell adhesion molecule | cell migration | chemotaxis | haematopoietic stem cell transplantation | haematopoietic stem cells | hypoxia

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