A novel Hepatitis B virus genotype in Indigenous Australians: impact on vaccine efficacy and clinical outcomes

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1060811

Funding Status
Closed

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Funded Activity Summary

We have recently identified a novel Hepatitis B virus (HBV) genotype (C4) circulating in Northern Territory (NT) Indigenous communities. Concurrently, epidemiological studies suggest that the HBV vaccine may not be working well and that there are high rates of liver cancer due to HBV in these communities. Our project will determine if HBV/C4 is linked to poor vaccine responses and accelerated liver disease, with implications for HBV vaccine strategy and clinical management of HBV/C4 infections.

Funded Activity Details

Start Date: 01-01-2014

End Date: 01-01-2017

Funding Scheme: Project Grants

Funding Amount: $1,100,960.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Aboriginal and Torres Strait Islander Health

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

epidemiology | hepatitis B virus | indigenous health | vaccine efficacy | virology

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