Airway epithelial injury and the innate lymphoid cell response in the pathogenesis of allergic asthma

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1060660

Funding Status
Closed

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Funded Activity Summary

Exposure to airborne particulate pollutants appears to contribute both to the development of childhood asthma and to acute severe attacks of asthma. We will investigate the mechanisms involved, using mouse models of childhood asthma and of asthma exacerbations. In particular, we will focus on the potentially critical role of a newly described population of host defence cells, and how these are activated as a result of injury of the lining cells of the airways.

Funded Activity Details

Start Date: 01-01-2014

End Date: 01-01-2016

Funding Scheme: Project Grants

Funding Amount: $607,559.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Respiratory Diseases

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

asthma | asthma exacerbation | environmental pollutants | epithelial cells | innate immunity | interleukins (IL)

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