Targeting the complement activation fragment C5a to improve the outcome from spinal cord injury

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1060538

Funding Status
Closed

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Funded Activity Summary

This project will focus on the development of a new drug that is designed to attenuate the harmful inflammatory response that follows from spinal cord injury (SCI). The experiments will determine if the therapeutic targeting of an immune receptor molecule, called C5aR, can protect compromised neural tissues after injury against harmful inflammation and degeneration whilst also explore the mechanism behind the therapeutic effect.

Funded Activity Details

Start Date: 01-01-2014

End Date: 01-01-2017

Funding Scheme: Project Grants

Funding Amount: $406,838.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Neurology and Neuromuscular Diseases

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

anti-inflammatory agents | complement activation | magnetic resonance imaging (MRI) | neuroinflammation | neuropathology | neuroprotection | spinal cord injury | spinal cord injury management

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