The identification and characterisation of a new DNA receptor

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1060522

Funding Status
Closed

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Funded Activity Summary

The immune system has evolved to fight disease-causing microbes. First, it has to recognize that an infectious agent has invaded. To do this we have developed many probes (receptors) that sense microbial products. Detecting microbial DNA is a critical alarm bell. However, distinguishing pathogen DNA from our own DNA is difficult because both look alike. We have identified a new receptor that helps us identify bacterial DNA and alerts the immune system to the imminent danger.

Funded Activity Details

Start Date: 01-01-2014

End Date: 01-01-2017

Funding Scheme: Project Grants

Funding Amount: $656,498.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Innate Immunity

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Toll-like receptors | adjuvant | dendritic cell | innate immunity | vaccine design

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