Targeting GDNF family ligand (GFL) signalling to treat inflammatory bone pain

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1060514

Funding Status
Closed

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Funded Activity Summary

Pain associated with bone marrow oedema syndromes, osteomyelitis, osteoarthritis, fractures and bone cancer causes a major burden on individuals and health care systems in Australia and worldwide. In this application, we will explore specific signalling pathways that we have identified in nerves that code bone pain. This will provide an opportunity for the rational design of highly specific drugs capable of interacting exclusively with molecules that drive pain in these conditions.

Funded Activity Details

Start Date: 01-01-2014

End Date: 01-01-2017

Funding Scheme: Project Grants

Funding Amount: $329,285.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Sensory Systems

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

bone | chronic pain | musculoskeletal | pain | sensory neurons

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