A novel mechanism for regulating membrane proteins by ubiquitin ligases and their adaptors

Funding Activity

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Funded Activity Summary

Many membrane proteins act as ion channels, transporters or receptors for extracellular ligands and are critical to normal functioning of the cell. These proteins are generally regulated by transport to or from the membrane to ensure that correct levels are maintained at the membrane. This proposal is to study a novel way of regulating membrane proteins. The successful completion of the work will provide important knowledge relevant to many human diseases.

Funded Activity Details

Start Date: 01-01-2014

End Date: 01-01-2016

Funding Scheme: Project Grants

Funding Amount: $627,897.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Receptors and Membrane Biology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

cell biology | membrane protein | ubiquitin-mediated proteolysis | ubiquitination | vesicle trafficking