A new paradigm for the control of cellular function: the dynamic reshaping of the epigenome by histone variants

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1058941

Funding Status
Closed

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Funded Activity Summary

Our DNA is packaged and partitioned into stable identities, chromosomes, which is critical for proper cell function and the inheritance of our genetic material from one cell generation to the next. Loss of chromosome integrity leads to cancer and therefore the cell must ensure that this does not happen. We have uncovered a new mechanism whereby different components of chromosomes can dynamically move from one location to another to ensure chromosomes remain stable when they are challenged.

Funded Activity Details

Start Date: 01-01-2014

End Date: 01-01-2017

Funding Scheme: Project Grants

Funding Amount: $672,735.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Biochemistry and Cell Biology not elsewhere classified

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

cell biology | chromatin | chromatin structure | epigenetics | transcriptional regulation

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