Molecular mechanisms in pregnancy-indcuded hypertension

Funding Activity

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Funded Activity Summary

Approximately 5-10% of pregnancies are complicated by hypertension with associated health risks for both mother and child. To keep blood pressure at normal levels during pregnancy requires active regulation, but underlying processes are not yet fully understood. We have identified a molecule which crucially controls blood pressure during pregnancy. In this proposal we will study how the molecule remodels blood vessels in pregnant females to optimize pharmacological intervention and pregnancy outcomes in humans.

Funded Activity Details

Start Date: 01-01-2014

End Date: 01-01-2017

Funding Scheme: Project Grants

Funding Amount: $649,668.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Cardiology (incl. Cardiovascular Diseases)

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

blood pressure regulation | mouse models | pregnancy complications | signalling pathways | vascular remodelling