Redox Control of the Immune Regulatory Protein, Indoleamine 2,3-dioxygenase

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1058508

Funding Status
Closed

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Funded Activity Summary

An enzyme called indoleamine 2,3-dioxygenase is important for controlling the immune system during normal and disease conditions including pregnancy, cancer, inflammation and infectious disease. Despite its importance little is known about how this enzyme is controlled. This project will provide important new insights into how this enzyme is regulated. Such fundamental scientific information can discover new ways in which to alter the enzyme's activity in order to modulate immune responses.

Funded Activity Details

Start Date: 01-01-2014

End Date: 01-01-2017

Funding Scheme: Project Grants

Funding Amount: $576,538.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Enzymes

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

T cell response | dendritic cell | enzyme regulation | enzyme structure | hydrogen peroxide | immune modulation | influenza virus | nitric oxide | redox regulation | spectroscopy

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