MLKL-regulated necroptosis pathways in disease

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1057905

Funding Status
Closed

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Funded Activity Summary

Only recently has it emerged that our cells have a built-in backup mechanism that instructs cells to die in extreme cases, such as when viruses have hijacked a cell. A misfiring backup mechanism is thought to underlie a number of human diseases, including inflammatory disease. Our investigation will establish a starting point for the development of novel anti-inflammatory drugs.

Funded Activity Details

Start Date: 01-01-2014

End Date: 01-01-2017

Funding Scheme: Project Grants

Funding Amount: $610,683.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Signal Transduction

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

cell death | death signalling | kinase inhibitors | kinases | necrosis | signal transduction | signalling pathways | structural biology

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