A theoretical framework for chemotherapy and immunosuppression

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1057831

Funding Status
Closed

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Funded Activity Summary

The team has discovered that potential alternative cell fates behave like autonomous timers, and are in competition in every cell. Variation in selected times within each cell alters the proportion that that die, divide or change into another cell type. The team have produced computational models of cell growth applicable to the immune response and cancer. Here they will apply their discovery to measure the effects of chemotherapeutic drugs and develop new protocols for enhancing the use of such drugs in the clinic.

Funded Activity Details

Start Date: 01-01-2014

End Date: 01-01-2016

Funding Scheme: Project Grants

Funding Amount: $561,028.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Applied Immunology (incl. Antibody Engineering, Xenotransplantation and T-cell Therapies)

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

cancer cell biology | drug efficacy | lymphocytes | lymphoma | mathematical modelling

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