The opposing genetic networks underlying plasticity of humoral responses

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1057707

Funding Status
Closed

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Funded Activity Summary

The immune system makes antibody to clear bacterial and viral pathogens. Specialised types of antibody are needed for different pathogens. This project will study genetic changes that determine the specificity of an antibody response. Regulation of these genes may prohibit production of antibodies and inflammatory mediators that attack the body rather than foreign pathogens. Understanding these processes will identify points of therapeutic intervention for patients with immune disorders.

Funded Activity Details

Start Date: 01-01-2014

End Date: 01-01-2018

Funding Scheme: Project Grants

Funding Amount: $667,783.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Humoural Immunology and Immunochemistry

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

B cells | antibody | chemokine receptor | humoral immunity | immunoglobulin (Ig) | immunologic memory | lymphocyte differentiation | lymphocyte migration | molecular immunology | transcription factor

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