Characterisation of the role of mesenchymal phenotypes and EGFR in treatment-resistant melanoma.

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/GNT1055456

Funding Status
Closed

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Funded Activity Summary

Phenotypic change has been identified in multiple settings relating to melanoma progression and metastasis. We have identified a degree of overlap between features of phenotypic plasticity, epithelial-to-mesenchymal transition, and the emergence of treatment resistance. This project will further examine mechanisms underlying these changes, focusing on the role of the epidermal growth factor.

Funded Activity Details

Start Date: 01-01-2013

End Date: 01-01-2016

Funding Scheme: Postgraduate Scholarships

Funding Amount: $113,237.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Molecular Targets

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

cancer cell biology | cancer treatment | epithelial-mesenchymal transition (EMT) | kinase inhibitors | melanoma

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