The role of Th17 and Tregs in the development of tolerance and rejection in a murine model of renal allograft rejection

Funding Activity

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Funded Activity Summary

In clinical transplantation, rejection remains the greatest problem in determining both short and long-term patient outcomes. Tolerance, the ability of the body to accept a transplant without immunosuppressive drugs, remains an as yet unattained goal. The aim of this project is to examine the mechanisms by which the initial immune response (innate immunity) affects the development of tolerance or rejection in a mouse model of kidney transplantation.

Funded Activity Details

Start Date: 01-01-2013

End Date: 01-01-2015

Funding Scheme: Postgraduate Scholarships

Funding Amount: $110,068.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Transplantation Immunology

ANZSRC Socio-Economic Objective (SEO)

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Other Keywords

immunology | mouse models | nephrology | renal transplantation | transplantation tolerance