Understanding the major class of cell surface drug targets

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/GNT1055134

Funding Status
Closed

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Funded Activity Summary

G Protein-Coupled Receptors (GPCRs) form the largest family of receptors and drug targets in living organisms. Currently, the major reason that new drugs fail to reach the clinic is lack of appropriate drug effect (approx. 30%). Thus, we need a better understanding of how GPCRs work and how this relates to disease. Our Program addresses this knowledge gap, using GPCR models that are relevant to treatment of metabolic, inflammatory, cardiovascular and central nervous system disease.

Funded Activity Details

Start Date: 01-01-2014

End Date: 01-01-2018

Funding Scheme: Program Grants

Funding Amount: $7,595,840.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Basic Pharmacology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

G protein-coupled receptors | drug discovery | drug efficacy | inflammatory diseases | metabolic disease | neuropsychiatric disorders | receptor signalling | receptor trafficking | signalling pathways

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