Characterization of H. pylori –specific CD4 T cell responses and the evaluation of the basic requirements for the development of an effective anti-H. pylori vaccine

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1055014

Funding Status
Closed

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Funded Activity Summary

H. pylori infect over half of the global population. Although infection results in asymptomatic gastritis in most cases 10 % develop gastric ulcers and cancer. Current vaccination strategies have failed to protect humans from infection. We aim to characterise the main immune cells involved in H. pylori infection, specifically the bacteria-specific CD4 T cells. We will then try to understand the basic requirements for a successful vaccine in order to develop new, improved anti-H. pylori vaccines.

Funded Activity Details

Start Date: 01-01-2013

End Date: 01-01-2017

Funding Scheme: Early Career Fellowships

Funding Amount: $313,161.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Cellular Immunology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Helicobacter pylori | T cells | gastric cancer | immune response | vaccine development

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