TIN2, HP1 and the cohesin complex in telomere cohesion in dyskeratosis congenita and human cancer cells

Funding Activity

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Funded Activity Summary

All cancers and premature aging syndromes such as dyskeratosis congenita (DC) are underpinned by defects in the functioning of telomeres. Telomeres are structures that protect the ends of human chromosomes from degradation. This project aims to determine if telomere function in these diseases is influenced by cohesion between DNA strands during cellular replication. The results may provide insights into factors controlling telomere function in DC and cancer cells.

Funded Activity Details

Start Date: 01-01-2013

End Date: 01-01-2018

Funding Scheme: Early Career Fellowships

Funding Amount: $388,335.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Biochemistry and Cell Biology not elsewhere classified

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

DNA replication | ageing | cancer | cancer biology | cancer research | cell biology | telomerase | telomeres

ACN 633 798 857