Scabies mite proteins as targets for the development of new therapeutics

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/GNT1054968

Funding Status
Closed

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Funded Activity Summary

Scabies and associated bacteria disease (pyoderma) are a significant health burden, with pyoderma implicated in rheumatic fever and heart disease. Investigations of the mechanism underlying scabies and bacteria disease links, identified scabies proteins inhibiting the human complement system. The inhibition prevents mite damage and promotes growth of bacteria. This proposal aims to elucidate the interaction between scabies, bacteria and the human host, in order to design new therapeutics.

Funded Activity Details

Start Date: 01-01-2013

End Date: 01-01-2018

Funding Scheme: Early Career Fellowships

Funding Amount: $299,564.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Medical Parasitology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Sarcoptes scabiei | Staphylococcus aureus | complement | indigenous health | serine proteases | skin infections

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