Regulation of the production of IgE antibodies by antigen-specific B cells

Funding Activity

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Funded Activity Summary

Our team has been studying the immune cells that make antibodies and recently discovered that cells without a particular gene make large amounts of IgE antibody. IgE is responsible for asthma and other allergies, which are a major cause of morbidity in the Western world. Based on this discovery, we aim to find out exactly how and why IgE is made in some circumstances but not others, and what other immune cells are involved. These results will identify a way to prevent asthma and other allergies.

Funded Activity Details

Start Date: 01-01-2013

End Date: 01-01-2018

Funding Scheme: Early Career Fellowships

Funding Amount: $330,662.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Humoural Immunology and Immunochemistry

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

B cells | adaptive immunity | antibody | germinal centre | humoral immunology