Investigating the gene and gene expression differences in the cells that drive leukemia development and relapse in children with AML

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/GNT1054482

Funding Status
Closed

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Funded Activity Summary

Current treatments for AML are initially effective at killing the majority of leukemic cells, but the disease often comes back (relapses) due to rare cells that escape treatment and can regenerate the cancer (called leukemic stem cells or LSC for short). This project aims to determine if an individual patient has one, or many kinds of LSC and which kind of LSC is most likely to cause relapse. We believe that this knowledge will lead to new treatments that can target the cells that cause relapse.

Funded Activity Details

Start Date: 01-01-2013

End Date: 01-01-2019

Funding Scheme: Early Career Fellowships

Funding Amount: $388,612.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Haematology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

acute myeloid leukaemia (AML) | cancer genetics | gene expression | gene mutations | haematological malignancy | haematopoiesis | haematopoietic stem cells | leukaemia

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