Structure-based Drug Design for Neuroprotection from Traditional Chinese Medicine

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1054172

Funding Status
Closed

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Funded Activity Summary

In the proposed research, three novo approaches for drug discovery will be explored: 1) The important neurodegenerative disease relevant protein JNK3 crystals will be used as the probe to fish out the potential inhibitors from Traditional Chinese Medicine (TCM); 2) Instead of individual drug components, the mixture of TCM will be used directly; 3) The composition of a TCM library are not randomly chosen but have been used in China for hundreds to thousands of years in curing neurodegenerative disease.

Funded Activity Details

Start Date: 01-01-2013

End Date: 01-01-2015

Funding Scheme: Early Career Fellowships

Funding Amount: $245,968.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Central Nervous System

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

drug screening | herbal medicines | kinase inhibitors | neurodegeneration | structure-based drug design

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