Identification and development of proteins which interact with the innate immune system as malaria vaccine candidates

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/GNT1053924

Funding Status
Closed

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Funded Activity Summary

Parasites causing malaria live inside red blood cells. Some human proteins act in a chain reaction to destroy infected cells. Although these proteins recognise parasite-infected cells and the chain reaction starts, the infected cells are not destroyed due to parasite proteins which inhibit the human proteins. A vaccine could induce antibodies which block the parasite proteins inhibiting the human proteins so the immune system can function normally and kill infected cells, thus stopping malaria.

Funded Activity Details

Start Date: 01-01-2013

End Date: 01-01-2019

Funding Scheme: Early Career Fellowships

Funding Amount: $299,564.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Medical Parasitology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Plasmodium falciparum | complement | immune evasion | malaria vaccine | vaccine candidate molecules | vaccine-preventable diseases

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