Dissecting the molecular mechanisms behind actin filament disassembly - an essential process in malaria parasite cell movement

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1053801

Funding Status
Closed

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Funded Activity Summary

The malaria parasite’s survival is reliant on efficient cell movement - a process that depends on the remodeling of the parasite actin cytoskeleton. The aim of this project is to understand how the actin cytoskeleton is disassembled when the parasite moves and to dissect the role of a key parasite protein, PfADF1, in the process. This project will elucidate fundamental insights into a key aspect of malaria parasite biology and, significantly, will shed light on how parasite movement can be inhibited.

Funded Activity Details

Start Date: 01-01-2013

End Date: 01-01-2016

Funding Scheme: Early Career Fellowships

Funding Amount: $311,860.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Medical Parasitology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

X-ray crystallography | actin | control of cell movement | infectious diseases | malaria

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