Mycobacterial control of the establishment and outcome of infection

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/GNT1053407

Funding Status
Closed

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Funded Activity Summary

Tuberculosis (TB) claims almost two million lives every year. TB subverts host immunity by directing the immune cells to launch an ineffective response to infection. One such trick is to hijack control of a class of molecules called eicosanoids from the host. This project will use a validated zebrafish model of TB infection to pinpoint the mechanisms used by mycobacteria to subvert normal eicosanoid production. Findings from this work may to aid the creation of novel anti-TB therapies.

Funded Activity Details

Start Date: 01-01-2013

End Date: 01-01-2018

Funding Scheme: Early Career Fellowships

Funding Amount: $311,956.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Medical Bacteriology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

immune evasion | immunology | lipoxygenase | mouse models | mycobacterial infection | phagocytes | zebrafish

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