Combined therapy to ameliorate ventilatory instability in patients with heart failure and sleep apnea

Funding Activity

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Funded Activity Summary

Sleep apnea is highly prevalent, particularly in patients with heart failure, and treatment remains limited to applying pressure via a face mask which can be intolerable. Although instability in breathing control is a major cause of apnea in many patients, treatments targeting instability with sufficient efficacy are unavailable. This project will combine two treatments, acetazolamide and oxygen, to powerfully reduce instability and provide relief from sleep apnea in a subgroup of patients.

Funded Activity Details

Start Date: 01-01-2013

End Date: 01-01-2019

Funding Scheme: Early Career Fellowships

Funding Amount: $386,648.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Systems Physiology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

control of breathing | heart failure | mechanism of action | sleep apnoea | treatment-resistant