A role for double-stranded RNA-dependent protein kinase in regulating Nod-like receptor signaling for modulating colitis and colitis-associated cancer.

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1052730

Funding Status
Closed

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Funded Activity Summary

Inflammatory bowel disease (IBD) and Colorectal cancers (CRC) are commonly found in developed countries like Australia. In spite of improved treatment for IBD and CRC, it is still not known why many patients are still not responsive to these therapies. Therefore, this proposed project aims to use genetically modified mice and molecular biology techniques to understand the pathogenesis of these diseases and to find an alternative new treatment for these diseases.

Funded Activity Details

Start Date: 01-01-2013

End Date: 01-01-2015

Funding Scheme: Early Career Fellowships

Funding Amount: $230,600.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Tumour Immunology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

colitis | colorectal cancer | colorectal cancer treatment | immune regulation | immune-mediated inflammation | inflammation | inflammatory bowel disease (IBD) | interleukins (IL) | macrophages | ulcerative colitis

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