Investigation of 5-methylcytosine and microRNA function in eukaryotic RNA

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1052182

Funding Status
Closed

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Funded Activity Summary

It is hypothesised that 5-methylcytosine in RNA represents a novel regulatory code affecting transcriptome utilisation in ways currently hidden from view. To unravel this code and its (patho)- physiological role(s), this study proposes to generate and interpret comprehensive transcriptome-scale maps of 5-methylcytosine in a range of cellular contexts chosen to reveal links to cellular differentiation, growth, and malignant transformation.

Funded Activity Details

Start Date: 01-01-2013

End Date: 01-01-2017

Funding Scheme: Early Career Fellowships

Funding Amount: $311,991.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Gene Expression (incl. Microarray and other genome-wide approaches)

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

RNA | RNA processing | cytosine methylation | eukaryotic gene expression | messenger RNA (mRNA) | microrna

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