A newly identified role for 14-3-3zeta protein in thrombosis and platelet procoagulant activity

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1050817

Funding Status
Closed

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Funded Activity Summary

Cardiovascular disease, including heart attack and stroke is the major cause of death globally, and is responsible for the death of 50,000 Australians each year. Platelet activation and blood coagulation play an important role in these diseases and we have discovered that a protein called 14-3-3 zeta is important in the processes that result in thrombosis. We are studying the mechanisms by which this protein contributes to life-threatening platelet activation with the aim of developing new and more effective anti-thrombotic drugs.

Funded Activity Details

Start Date: 01-01-2013

End Date: 01-01-2015

Funding Scheme: Project Grants

Funding Amount: $556,327.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Haematology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

coagulation | collagen | embolism | mouse models | platelet function | receptor signalling | thrombin | thrombosis

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