New High Thoughput Animal Models to Investigate Amyloid Beta Toxicity

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1050751

Funding Status
Closed

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Funded Activity Summary

Amyloid-beta is widely considered to cause Alzheimer’s disease. The majority of amyloid-beta in Alzheimer's disease brains is found as shortened forms. The role of these shortened forms is uncertain and are not being tested in current animal models. We propose to develop new models to determine and compare their respective toxic effects, and to use these new models to help identify drugs to treat Alzheimer's disease.

Funded Activity Details

Start Date: 01-01-2013

End Date: 01-01-2015

Funding Scheme: Project Grants

Funding Amount: $402,223.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Biochemistry and Cell Biology not elsewhere classified

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Alzheimer disease | amyloid beta-protein | disease modelling | disease prevention | drug screening | neurodegeneration

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