KRAS- and BRAF-Mediated Methylation Signatures in Colorectal Cancers and Polyps

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1050455

Funding Status
Closed

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Funded Activity Summary

Bowel cancer is one of the most common cancers affecting Australians. We hypothesise that there are different types of bowel cancer depending on different genes that can be inactivated abnormally, and these subgroups have different clinical features and responses to therapy. We aim to identify the major gene changes that characterise these subgroups, which will in the future allow the development of gene markers for early detection as well as the possibility of individualised patient therapy.

Funded Activity Details

Start Date: 01-01-2013

End Date: 01-01-2015

Funding Scheme: Project Grants

Funding Amount: $457,076.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Gastroenterology and Hepatology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

RAS oncogenes | colonoscopy | colorectal | methylation | molecular pathogenesis

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