Clinical implications of IL7R genotype: from disease risk to disease management

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1050074

Funding Status
Closed

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Funded Activity Summary

We’ve identified a genetic test (IL7R?) that may predict and prevent the risk of patients (i) failing to respond adequately to treatment for HIV (ii) who are at high risk of death after bone marrow transplantation and (iii) who fail to respond to interferon treatment for MS. This project aims to confirm these in very large patient groups and uncover the cellular basis for the genetic effect. Our goal is to provide a novel test that will improve patient outcomes in 3 serious disease states.

Funded Activity Details

Start Date: 01-01-2013

End Date: 01-01-2016

Funding Scheme: Project Grants

Funding Amount: $627,765.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Genetic Immunology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

CD4 | antiretroviral therapy | bone marrow transplantation | genetics | human immunodeficiency virus (HIV) | interferon non-responders | interleukins (IL) | multiple sclerosis (MS) | pharmacogenomics | regulatory T cells

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