Developing functionalised microbubbles for molecular ultrasound imaging and targeted delivery of drugs and microRNA therapeutics

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1050018

Funding Status
Closed

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Funded Activity Summary

We aim to develop gas-filled microbubbles that are directed to markers of thrombosis and inflammation and will allow visualisation of blood clots and early inflammatory reactions via ultrasound. This will allow early and timely treatment. We will systematically test for the best method of microbubble coating with recombinant antibodies in various animal models of thrombosis and inflammation. In addition, we plan to load microbubbles with drugs and target these to areas where they are needed.

Funded Activity Details

Start Date: 01-01-2013

End Date: 01-01-2016

Funding Scheme: Project Grants

Funding Amount: $677,229.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Cardiology (incl. Cardiovascular Diseases)

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

antibody | arthritis | drug delivery systems | inflammation | molecular imaging | recombinant engineering | targeted therapy | thrombosis | translational research | ultrasound

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