How do the Vitamin D Receptor activation genes CYP27B1 and CYP24A1 alter susceptibility to autoimmune diseases?

Funding Activity

Does something not look right? The information on this page has been harvested from data sources that may not be up to date. We continue to work with information providers to improve coverage and quality. To report an issue, use the .

Funded Activity Summary

Because Vitamin D deficiency has long been associated with autoimmune diseases, clinical trials with various forms of Vitamin D have been conducted and are underway. Yet the basis for the Vitamin D association has not been established. In 2012, two vitamin D genes were shown to alter susceptibility to autoimmune diseases. The goal of this project is to determine how these genes influence immune tolerance mechanisms, and so develop novel and improved therapeutic approaches based on Vitamin D.

Funded Activity Details

Start Date: 01-01-2013

End Date: 01-01-2016

Funding Scheme: Project Grants

Funding Amount: $508,518.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Gene Expression (incl. Microarray and other genome-wide approaches)

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

autoimmune disease | gene expression | immunogenetics | multiple sclerosis (MS) | vitamin D