Molecular Characterization of V-ATPase V0 Domain Subunits e1 and e2 in Osteoclast

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1049884

Funding Status
Closed

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Funded Activity Summary

Osteoporotic fractures in the elderly are often linked to increased mortality rates. Excess bone resorption is a major contributor to the onset of the disease. The proposed project focuses on the investigation of the molecular mechanisms of acid secretion that is required for the bone degradation in body. The project will examine the role of the proton pump in bone resorption and seek potential targets for the treatment of osteoporosis.

Funded Activity Details

Start Date: 01-01-2013

End Date: 01-01-2015

Funding Scheme: Project Grants

Funding Amount: $558,909.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Orthopaedics

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

bone biology | knockout mouse | osteoclast | osteoclastogenesis | osteolysis

Related Links