Role of exported proteins in malaria parasite development in the liver

Funding Activity

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Funded Activity Summary

Each year over 250 million people contract malaria and over 1 million die. The key to the malaria parasite’s success is the ability to live inside host cells, including hepatocytes and erythrocytes. Here, we aim to determine how the malaria parasite lives within hepatocytes, to engineer mutant parasites that can no longer do so and to assess whether mutant parasites confer protection against future malaria. Our program will use the most virulent human parasite P. falciparum and the rodent parasite P. berghei.

Funded Activity Details

Start Date: 01-01-2013

End Date: 01-01-2015

Funding Scheme: Project Grants

Funding Amount: $520,613.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Protein Trafficking

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

cell biology | host/pathogen interaction | malaria | protein trafficking | virulence