How Deletional and Non-Deletional Tolerance Mechanisms Integrate to Prevent Autoimmune Disease

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1049724

Funding Status
Closed

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Funded Activity Summary

The body produces millions of immune cells every day to fight infection. Some of these immune cells are defective and dangerous because they can cause autoimmune diseases, like Type I diabetes and multiple sclerosis. To defuse this risk, such immune cells are either caused to die or are inactivated to prevent autoimmunity. We propose to investigate how the processes of immune cell death and inactivation work in health and disease so we may harness these mechanisms to cure autoimmunity.

Funded Activity Details

Start Date: 01-01-2013

End Date: 01-01-2015

Funding Scheme: Project Grants

Funding Amount: $509,944.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Autoimmunity

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

T cells | apoptosis | autoimmune disease | autoimmunity initiation | tolerance

Related Links