Molecular control of cell proliferation in early mouse development

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/104948

Funding Status
Closed

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Funded Activity Summary

Elucidation of cell cycle regulation in the proliferating pluripotent cells of the early mammalian embryo is likely to have important impact on basic scientific knowledge, and on the development of novel therapeutic strategies. Investigation of this problem, in vitro and in vivo, requires specialist skills in cell cycle analysis, and experimental manipulation of mammalian embryos and pluripotent cells. This application will seek to address these fundamental issues of early development and cell proliferation using molecular approaches. The general aims will be: 1. to obtain a detailed description of cell cycles in pluripotent and differentiating cells of the mouse embryo 2. use this information to build a molecular description of cell cycle events during early embryogenesis 3. investigate the relationship between rapid cell proliferation in the embryo and pluripotency

Funded Activity Details

Start Date: 01-01-2000

End Date: 01-01-2002

Funding Scheme: NHMRC Project Grants

Funding Amount: $338,009.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Cell Development (Incl. Cell Division And Apoptosis)

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

cancer | cell cycle | cell proliferation | development | differentiation | early development | embryogenesis

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