Viewing the cellular responses in Huntington’s disease through an aggreomics framework

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1049458

Funding Status
Closed

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Funded Activity Summary

Huntington disease results from a mutation that causes the Htt protein to form abnormal toxic clusters in neurons that eventually leads to cell death. This project will develop and apply new technology to identify how the clustering process damages cells and will measure all the gene expression changes that occur during the clustering process. The project offers much potential for revealing new therapeutic targets to this incurable disease.

Funded Activity Details

Start Date: 01-01-2013

End Date: 01-01-2016

Funding Scheme: Project Grants

Funding Amount: $363,218.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Cell Metabolism

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Huntington's disease | amyloid | biomarkers | biosensor | protein aggregation

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