The roles of the transcriptional regulators Id2 and Id3 in plasma cell differentiation and B cell memory

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1049416

Funding Status
Closed

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Funded Activity Summary

Antibody producing cells and memory B cells are crucial to successful vaccination and provide protection against infections. Development of both is controlled by factors that regulate gene activity, but the same factors are also involved in the development of blood cancers. Using new research tools and assays we will uncover the roles of the Id and E protein family of factors implicated in these processes, which may help in the design of new vaccination strategies and the treatment of blood cancers.

Funded Activity Details

Start Date: 01-01-2013

End Date: 01-01-2015

Funding Scheme: Project Grants

Funding Amount: $438,951.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Immunology not elsewhere classified

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

B cells | antibody | germinal centre | transcriptional regulation | vaccination immunology

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